NAM IN A VANDER WOUDE SYNDROME

Abstract

Introduction::The Vander Woude syndrome is an autosomal-dominant condition typically comprising cleft lip or cleft palate or both and distinctive pits of the lower lips. The degree to which individuals carrying the gene are affected varies widely, even within families. The variable manifestations include lip pits alone, hypodontia (absent teeth), and isolated cleft lip and palate of varying degrees of severity.

Case History. A case of Van Der Woude Syndrome 24 days old, characterized by pits on the lower lip and bilateral cleft of the lip and palate with similarly affected mother is presented.

Progress: Presurgical infant orthopedics was done to reduce the severity of the initial cleft alveolar and nasal deformity. NAM therapy resulted in better lip and nasal form, reduced oronasal fistula and labial deformities and it also causes 60 % reduction in the need for secondary alveolar bone grafting. After NAM primary lip repair was carried out.

Conclusion: VDW is under reported & frequently not diagnosed. The phenomena that CLP & CP are regularly combined in the same pedigree makes it unique. A multidisciplinary approach to treatment produced an aesthetically pleasing and functional outcome.